Stoke defender Andy Wilkinson is ruled out of Saturday's game because of a knee injury.
Striker Kenwyne Jones will hope for a recall after scoring as a substitute against Birmingham in midweek.
Southampton will assess Dani Osvaldo and Steven Davies, but the duo are likely to be available despite missing out last weekend with minor injuries.Watch Stoke V Southampton Live,Watch Stoke V Southampton Live Stream, Watch Stoke V Southampton Free Live Stream, Watch Stoke V Southampton Online, Watch Stoke V Southampton Online Free, Stoke V Southampton Live, Stoke V Southampton live stream Online.
However, midfielder Guly do Prado is expected to be sidelined because of a knee problem.
MATCH PREVIEW
A year ago Southampton slumped to the bottom of the table after a truly dreadful start to life in the top echelon.
Inevitably, there was talk of an immediate return to the Championship. Twelve months on and they are riding high above both Manchester clubs. A six-match unbeaten run leaves them fifth. It is quite a story. But if Southampton are flying, Stoke are trundling along the runway, waiting for permission to take-off.
They haven't won a league game since August, and have lost four of their last five.
Okay, last week they rose to the occasion and very nearly pulled off the club's first win at Manchester United since 1976.
But instead of making history they made a mess of it, missing chances then defending badly to allow Wayne Rooney and Javier Hernandez to put a smile back on the face of David Moyes.
On Tuesday night they nearly blew it again, losing a 3-1 lead against ten men with five minutes to go before scraping past Birmingham in a penalty shoot-out to reach the last eight of the League Cup.
Such defensive shortcomings will be eagerly exploited by a Southampton side enjoying their best start to a top-flight season. Remember, they scored late on to get a point at Old Trafford and won at Anfield in what is Liverpool's only defeat of the season.
The strength of Mauricio Pochettino's team is their defensive work. They've only conceded three goals, the best record in the Premier League, and Artur Boruc has only been beaten by Robin van Persie in his last six games.
The odds on another clean sheet for the Poland international should be slim. The Britannia faithful haven't seen their team score since 24 August. That was during Mark Hughes' honeymoon period, but it didn't last long.
To avoid speculation of a speedy divorce he needs something from this one to stop the rot.
MATCH FACTS
Head-to-head
Stoke's last top-flight win at home to Southampton was a 4-1 victory in March 1974.
Last season's corresponding fixture, held on 29 December, ended 3-3. That is the last time Stoke scored more than twice in a Premier League game.
Stoke City
The Potters have averaged 1.67 points per Premier League match in the month of November - a ratio bettered by only Manchester United and Chelsea.
Stoke have failed to win their last six league games. No top-flight side is on a longer winless run (Crystal Palace are also winless in six matches).
The Potters have only conceded four goals in their last six home league games.
This will be Stoke's 200th Premier League match (W58, D59, L82).
Marko Arnautovic has not won on any of his 18 league appearances in 2013 - more than any other player in one of the top five European leagues. That includes six matches with Stoke and 12 with Werder Bremen.
Southampton
Their haul of 18 points from nine games represents their best start to a top-flight season.
Saints have kept a clean sheet in all but one of their last six league games.
They have the best defensive record in the Premier League. Their total of three goals conceded is their lowest tally after nine top-flight fixtures.